{"product_id":"argalys-pre-collagene-vegan-pd-0366","title":"Argalys — Vegan Pre-Collagen · Coll-Egan® + Hyaluronic Acid","description":"\u003cp\u003eCollagen accounts for approximately 25 to 35% of the body's total protein. Its endogenous production decreases by about 1% per year from the age of 30, gradually contributing to visible and functional changes in connective tissue. A fundamental nuance is essential before discussing supplementation: ingested collagen (bovine, marine, or other) is digested into peptides and then into free amino acids before any intestinal absorption. The body does not transport intact collagen to the skin or joints. The synthesis of tissue collagen depends exclusively on endogenous biosynthesis mechanisms and the availability of substrates.\u003c\/p\u003e\n\u003cp\u003eWhat the body requires to synthesize its own collagen involves three elements: sufficient availability of glycine (an amino acid representing ~30% of collagen's composition, often underrepresented even in protein-rich diets because it is mainly found in less commonly consumed connective tissues), sufficient availability of proline, and the proper functioning of the prolyl-hydroxylase and lysyl-hydroxylase enzymes, whose activity directly depends on vitamin C. It is this mechanistic logic—supporting endogenous biosynthesis rather than providing an exogenous protein—that the Argalys Pre-Collagen formula implements.\u003c\/p\u003e\n\u003cp\u003eVitamin C contributes to normal collagen formation for the normal function of skin, bones, and cartilage. It contributes to the protection of cells from oxidative stress. Zinc contributes to the maintenance of normal skin and normal bones.\u003c\/p\u003e\n\u003cp\u003eThe formula is based on five complementary active ingredients. Coll-Egan® (400 mg per 2 capsules) is a patented ingredient combining glycine, proline, hydroxyproline, glutamic acid, alanine, arginine, natural vitamin C from acerola, and bamboo shoot extract rich in ortho-silicic acid—according to the manufacturer Argalys, this ingredient benefits from a claim validated by EFSA for the role of vitamin C in normal collagen formation. Free Glycine (300 mg) and Free Proline (100 mg) are supplied separately in addition to Coll-Egan® to enrich the formula with directly absorbable amino acids. Vitamin C (50 mg = 63% NRV) participates in the activity of collagen maturation enzymes. Zinc (2.6 mg = 26% NRV) contributes to the enzymatic functions of tissue renewal. Hyaluronic Acid (150 mg) completes the formula: a macromolecule naturally present in the dermis and synovial fluid, several randomized clinical trials on this ingredient have documented an improvement in certain objective parameters of skin hydration and joint comfort after several weeks of oral supplementation (studies Oe et al. 2017, Kalman et al. 2008 — data on the ingredient, not specifically on this finished product). HPMCellulose vegetable capsule. Certified vegan by The Vegetarian Society. Made in France.\u003c\/p\u003e\n\u003cp\u003eAdults only. 2 capsules daily with a large glass of water, during a meal, away from tea and coffee. 60 capsules = 1 month's supply. A minimum 3-month course is recommended to observe effects on skin and connective tissues. Pregnant and breastfeeding women: seek medical advice before any supplementation.\u003c\/p\u003e","brand":"Argalys","offers":[{"title":"Default Title","offer_id":53856508608849,"sku":"PD-0366","price":23.9,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1032\/7094\/1009\/files\/argalys-pre-collagene-vegan-pd-0366-1-hd.jpg?v=1788396030","url":"https:\/\/paradermia.com\/en\/products\/argalys-pre-collagene-vegan-pd-0366","provider":"Paradermia","version":"1.0","type":"link"}