{"product_id":"numbuzin-no9-nad-plus-bio-lifting-sil-essence-50ml-pd-0486","title":"Numbuzin — No.9+ NAD+ BIO Lifting-sil Essence 50ml","description":"\u003cp\u003eLoss of skin firmness results from multiple biological mechanisms: progressive slowing of cell renewal, decreased density of the dermal collagen and elastin network, and increased lipid peroxidation due to free radicals. The most comprehensive formulation approaches aim to act simultaneously on several of these mechanisms. The active ingredient density here is pushed to its maximum: over 100 ingredients, including more than 50 distinct peptides.\u003c\/p\u003e\n\u003cp\u003eNumbuzin's No.9+ NAD+ BIO Lifting-sil Essence is based on NAD+ (Nicotinamide Adenine Dinucleotide), a central coenzyme in cellular metabolism whose levels decline with age. In topical cosmetics, the manufacturer combines it with ATP (Adenosine Triphosphate) in a NAD+ BIO complex (NAD+, ATP, Resveratrol), described as supporting skin cell energy. This complex is supplemented by a network of 50+ peptides targeting different aspects of dermal structure: signaling peptides (Tripeptide-1, Palmitoyl Pentapeptide-4), muscle contraction peptides (Acetyl Hexapeptide-8, Dipeptide Diaminobutyroyl Benzylamide Diacetate), repair peptides (Copper Tripeptide-1, Biotinoyl Tripeptide-1), and extracellular matrix peptides (Palmitoyl Dipeptide-5, Palmitoyl Tetrapeptide-7).\u003c\/p\u003e\n\u003cp\u003eThe formula's antioxidant power is provided by the combination of Astaxanthin (Haematococcus Pluvialis Oil), Resveratrol, Glutathione, Thioctic Acid (alpha-lipoic acid), and CoQ10 (Ubiquinone). Adenosine complements the firming action. Five Saccharomyces ferments (Copper, Iron, Magnesium, Silicon, Zinc) provide additional biological support. The manufacturer's clinical study, conducted over 4 weeks, reports a visible improvement in the appearance of 11 types of wrinkles (forehead wrinkles, frown lines, crow's feet, dark circles, bunny lines, lip wrinkles, smile lines, marionette lines, mental crease, chin wrinkles, and neck wrinkles). Manufacturer data — protocol and sample sizes not disclosed.\u003c\/p\u003e\n\u003cp\u003eApply an appropriate amount to the entire face morning and evening, after cleansing and toning, before moisturizer. For enhanced targeted action on areas with pronounced wrinkles (nasolabial folds, forehead wrinkles), reapply a second layer to these areas and massage gently until fully absorbed. The velvety texture (\"Lifting-sil\") penetrates without residue or stickiness.\u003c\/p\u003e\n\u003cp\u003eFragrance-free and alcohol-free formula. The presence of Chlorhexidine Digluconate (antiseptic preservative, EU Annex V) is unusual in a face essence – caution is advised for individuals with a history of reactions to chlorinated antiseptics. Certified vegan. Not recommended during pregnancy as a precaution (highly complex formula, specific safety data for pregnancy not available).\u003c\/p\u003e","brand":"Numbuzin","offers":[{"title":"Default Title","offer_id":53909777580369,"sku":"PD-0486","price":33.9,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1032\/7094\/1009\/files\/numbuzin-no9-nad-plus-bio-lifting-sil-essence-50ml-pd-0486-square.jpg?v=1780168113","url":"https:\/\/paradermia.com\/en\/products\/numbuzin-no9-nad-plus-bio-lifting-sil-essence-50ml-pd-0486","provider":"Paradermia","version":"1.0","type":"link"}