Argalys — Calcium + Vitamin D3 and K2 MK7

Argalys's calcium + D3 + K2 formula follows a logical, documented approach to bone supplementation. The three active ingredients work in sequence: vitamin D3 improves intestinal calcium absorption and circulation; vitamin K2 (menaquinone MK7) activates bone proteins (osteocalcin) that bind calcium to the matrix and direct circulating calcium towards bones rather than arteries. This D3-K2 synergy is well-documented in the bone and cardiovascular health literature. Calcium carbonate is the most concentrated form of elemental calcium (~40% vs ~21% for citrate) – an advantage for capsule volume. Its bioavailability is lower than citrate or bisglycinate when taken on an empty stomach, but equivalent when taken with a meal (gastric acidity ionizes the carbonate, forming absorbable calcium chloride). Taking this product during a meal is therefore essential. The D3 from boreal lichen is identical to that in Vitamin D3 Spray – same certified vegan plant source, same cholecalciferol molecule. Vitamin K2 is in the menaquinone MK7 form (long half-life, superior tissue distribution compared to MK4). The chosen dosages are moderate and suitable for preventive supplementation: 35 µg of K2 and 5 µg of D3 per 3 capsules. Critical drug interaction: Menaquinone vitamin K2 directly interacts with anticoagulant VKAs (warfarin, acenocoumarol, fluindione) which specifically exert their action by inhibiting the vitamin K-dependent pathway. Any variation in vitamin K intake can alter INR. This product is contraindicated or requires close INR monitoring in patients on VKAs – to be aware of before use. At 720 mg of calcium (90% NRV) per 3 capsules, the dosage is moderate and safe for a healthy person. However, individuals with chronic kidney failure, hypercalciuria, or a history of calcium stones should seek medical advice before any calcium supplementation.